McKesson Clinical Reference Systems: Women's Health Advisor 2002.2

Cytomegalovirus During Pregnancy

What is cytomegalovirus?

Cytomegalovirus (CMV) is a common viral infection that a baby can get from the mother before or during birth. If you have this infection during pregnancy, it can harm the baby.

How does it occur?

CMV is caused by a virus. The virus is spread from person to person through contact with infected saliva, blood transfusions, breast milk, urine, and semen. Often adults become infected from contact with young children who have the virus. If you are infected with the virus for the first time during pregnancy, your baby may become infected.

What are the symptoms?

CMV usually does not cause any symptoms. Sometimes you may have flulike symptoms such as swollen glands and tiredness.

Most infected babies do not show any symptoms at birth, but many develop problems later. Newborns infected with CMV before birth may have or develop the following problems:

  • small size
  • small brain
  • enlarged liver and spleen
  • hearing loss or eye problems
  • jaundice (yellowish skin)
  • calcium deposits in the brain
  • extra fluid that puts pressure on the brain.

How is it diagnosed?

A routine ultrasound may show something abnormal in the baby. Your health care provider will test samples of your blood 3 or 4 weeks apart. A sample of urine, cells from your cervix, or amniotic fluid may also be tested. Samples of the baby's urine, saliva, or other tissue may be tested for the virus.

How is it treated?

A baby infected with CMV might be treated with ganciclovir or hyperimmune gamma globulin.

How long will the effects last?

You may feel the effects of the illness for about 2 or 3 weeks, depending on your general health.

A child born with a CMV infection may have lifelong mental retardation, deafness, or other birth defects.

What can I do to help prevent infection with CMV?

You may be able to prevent becoming infected with CMV by avoiding contact with the saliva and urine of other people, especially of young children. Wash your hands thoroughly with soap and water after you have been around young children. Also, a vaccine has been developed that appears to be safe and protective.


Developed by McKesson Clinical Reference Systems.
Published by McKesson Clinical Reference Systems.

This content is reviewed periodically and is subject to change as new health information becomes available. The information is intended to inform and educate and is not a replacement for medical evaluation, advice, diagnosis or treatment by a healthcare professional.

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