McKesson Clinical Reference Systems: Women's Health Advisor 2002.2

Paget's Disease of the Nipple

Paget's disease is a type of breast cancer. With proper treatment it can be cured. In this discussion of Paget's disease you will learn what Paget's disease is, the symptoms of Paget's disease, and how your doctor will diagnose and treat it.

What is Paget's disease of the nipple?

Paget's disease is a slowly growing cancer of the nipple. It is a rare cancer, accounting for only 1 percent of all breast cancers.

How does it occur?

When abnormal cells grow uncontrollably, they are called tumors. It is not known why they occur. In Paget's disease, the tumor starts in the milk ducts of the nipple.

What are the symptoms?

One of the biggest problems with Paget's disease of the nipple is that its symptoms appear to be harmless. It is frequently thought to be a skin inflammation or infection, leading to unfortunate delays in detection and care. The symptoms include:

  • A persistent redness, oozing, and crusting of your nipple causing it to itch and burn.
  • A sore on your nipple that will not heal.
  • Usually only one nipple is affected.

How is it diagnosed?

Your doctor will do a physical exam and ask you about your history of illnesses. Even though the redness, oozing, and crusting closely resemble dermatitis (inflammation of the skin), your doctor will suspect cancer if the sore is only on one breast.

Your doctor will order a biopsy of your sore to confirm the diagnosis. A biopsy is a procedure in which the doctor takes a sample of your breast tissue to test for cancer. A mammogram (x-ray) of both breasts will be done to look for other cancers.

How is it treated?

If the cancer is only in the nipple and not in the breast, your doctor may recommend just removing the nipple and surrounding tissue or suggest radiation treatments.

If a mass is found deep in your breast, your doctor will discuss treatment alternatives, including surgery, radiation, and chemotherapy.

How long will the effects of Paget's disease last?

The cancerous sore will remain on your nipple and may spread deeper into your breast unless you have surgical treatment or radiation treatments. Your doctor will advise you as to the best treatment for your disease.

What can be done to help prevent this from recurring?

Check monthly for any lumps, sores, or oozing from your breasts and report any breast changes to your doctor immediately.


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Published by McKesson Clinical Reference Systems.

This content is reviewed periodically and is subject to change as new health information becomes available. The information is intended to inform and educate and is not a replacement for medical evaluation, advice, diagnosis or treatment by a healthcare professional.

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